Transcranial Magnetic Stimulation for Catatonia: Cases Serie
https://doi.org/10.52667/2712-9179-2023-3-1-66-78
Abstract
The article presents the results of transcranial magnetic stimulation of dorsolateral prefrontal cortex (DLPFC) in four patients with catatonia. The uniqueness of these observations arises from three factors. First, rehabilitation neuromodulation of catatonia was used in a personalized course of exposure to magnetic pulses, considering the intensity of regional cerebral blood flow (rCBF) in the affected area. Secondly, the entire course of treatment was carried out on an outpatient basis. Thirdly, the content of Gamma-aminobutyric-acid (GABA) and glutamate in the cerebral cortex was additionally studied before and after the course of transcranial magnetic stimulation (TMS). All four patients were diagnosed with catatonia as part of schizophrenia spectrum disorders in three cases and in one case within the structure of recurrent depression phase. All patients took monotherapy with atypical antipsychotics as the main psychopharmacotherapy, were compliant and gave informed voluntary consent. The effectiveness of TMS was recorded in three cases. There were no adverse events or complications in all 20 sessions.
About the Authors
N. V. Zakharova
Mental-health Clinic No. 1 named after N.A. Alexeev
Russian Federation
Russian Federation
Natalia V. Zakharova
Moscow
G. S. Mamedova
Mental-health Clinic No. 1 named after N.A. Alexeev
Russian Federation
Russian Federation
Galina S. Mamedova
Moscow
M. A. Shkurinova
Mental-health Clinic No. 1 named after N.A. Alexeev
Russian Federation
Russian Federation
Maria A. Shkurinova
Moscow
S. I. Kartashov
National Research Center Kurchatov Institute
Russian Federation
Russian Federation
Sergey I. Kartashov
Moscow
A. Zaborin
National Research Center Kurchatov Institute
Russian Federation
Russian Federation
Alexander Zaborin
Moscow
V. A. Orlov
National Research Center Kurchatov Institute
Russian Federation
Russian Federation
Vyacheslav A. Orlov
Moscow
Y. I. Kholodny
National Research Center Kurchatov Institute
Russian Federation
Russian Federation
Yuriy I. Kholodny
Moscow
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Review
For citations:
Zakharova N.V., Mamedova G.S., Shkurinova M.A., Kartashov S.I., Zaborin A., Orlov V.A., Kholodny Y.I. Transcranial Magnetic Stimulation for Catatonia: Cases Serie. Personalized Psychiatry and Neurology. 2023;3(1):66-78. https://doi.org/10.52667/2712-9179-2023-3-1-66-78
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